The George Washington University and the U.S. Food and Drug Administration published an update to the BioCompute Object Specification Project, which provides much-needed standards for communicating high-throughput sequencing computations and data analysis, known as BioCompute Objects.
This week, how to avoid contaminating Mars with microbial hitchhikers, turning mammalian cells into biocomputers, and a look at how underground labs in China are creating synthetic opioids for street sales in the United States with Online News Edi
The arms race between pathogen and host is a well-known phenomenon. Ma et al. have now identified how an enzymatically inactive protein can abet a pathogen's infectivity. The pathogenic oomycete Phytophthora sojae secretes xyloglucanase that damages soybean cell walls. Soybean, in turn, secretes a defense protein that binds to and inactivates the xyloglucanase. To counteract this plant defense, the oomycete deploys a product of its own gene duplication: an inactive enzyme that binds the plant's defense protein. With the defense protein unproductively bound to the decoy, the oomycete can successfully invade the soybean cells.
Science , this issue p.